Luminesce Alliance

Our outstanding researchers and clinicians are increasing capacity for rare disease research, innovation and equitable access to health system support for children with rare diseases and their families.

Find out more about our rare disease research

‘Having a child with a rare, complex condition is very isolating,’ says Kris Pierce whose son Will was finally diagnosed with the rare genetic disease SCN2A-related disorder when he was 14. “We can invest millions of dollars but we also need to provide families and healthcare professionals with psychosocial support.”

Kris and Will's story

Grace is a fun-loving, kind and inquisitive eight-year-old girl who lives with ADCY5-related movement disorder syndrome, an ultra-rare genetic condition. Hear from Grace’s mother Emma and A/Prof Wendy Gold about how the Luminesce Alliance Functional Genomics Platform is supporting discovery to improve Grace’s function.

Emma and Grace's story

Children’s Precision Medicine Research

Researchers

We work with researchers and clinicians to find answers for children living with cancers, rare genetic diseases and neurological disorders.

Families

Find out how precision medicine can help children with cancers, neurological disorders and rare diseases.

Collaboration

Our project teams work in a highly networked environment extending to collaboration with more than 50 organisations. For more information view the opportunities below and visit collaboration opportunties.

Our research is helping to find answers

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Luminesce Alliance brings together world-leading paediatric precision medicine researchers and clinicians to help find answers for children living with cancers, rare genetic diseases and neurological disorders.

Psychosocial Enabling Platform

Health Systems Implementation and Economics

THINK Drug Discovery

Functional Genomics Research Pipeline

Translational Tumour Biology

Kids Advanced Therapeutics

Kids Link

Collaboration Opportunities

INFORM2 (INdividualized Therapy for Relapsed Malignancies in Childhood)

E-2CAR Phase I clinical trial to evaluate administration of EphA2 targeted CAR T-cells to children with sarcoma

News and events

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Luminesce Alliance 2025 Impact Report - Driving collaboration to deliver precision medicine for every child

Paediatric cancers, rare diseases, and neurodevelopmental disorders affect thousands of children in NSW, placing a heavy burden on families and the health system. These conditions are often hard to treat and attract limited funding due to their rarity. Luminesce Alliance, with the support of NSW Health, drives precision medicine research tailored to children’s unique genetic

Harnessing AI and Big Data to transform childhood cancer care

Save the date and partner with us!

Did you know Luminesce Alliance has supported more than 200 research publications in leading journals?

Collaboration to impact: transforming paediatric healthcare with advanced therapies

Our partners and collaborators

Luminesce Alliance – Innovation for Children’s Health is a not-for-profit cooperative joint venture established with the support of the NSW Government to coordinate and integrate paediatric research.